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Transposon-modified antigen-specific T lymphocytes for sustained therapeutic protein delivery in vivo
A cell therapy platform permitting long-term delivery of peptide hormones in vivo would be a significant advance for patients with hormonal deficiencies. Here we report the utility of antigen-specific T lymphocytes as a regulatable peptide delivery platform for in vivo therapy. piggyBac transposon m...
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| Udgivet i: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5893599/ https://ncbi.nlm.nih.gov/pubmed/29636469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03787-8 |
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