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Evaluating the potential for undesired genomic effects of the piggyBac transposon system in human cells

Non-viral transposons have been used successfully for genetic modification of clinically relevant cells including embryonic stem, induced pluripotent stem, hematopoietic stem and primary human T cell types. However, there has been limited evaluation of undesired genomic effects when using transposon...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Saha, Sunandan, Woodard, Lauren E., Charron, Elizabeth M., Welch, Richard C., Rooney, Cliona M., Wilson, Matthew H.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4330379/
https://ncbi.nlm.nih.gov/pubmed/25605795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv017
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