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Evaluating the potential for undesired genomic effects of the piggyBac transposon system in human cells
Non-viral transposons have been used successfully for genetic modification of clinically relevant cells including embryonic stem, induced pluripotent stem, hematopoietic stem and primary human T cell types. However, there has been limited evaluation of undesired genomic effects when using transposon...
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Publicado en: | Nucleic Acids Res |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado: |
Oxford University Press
2015
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Assuntos: | |
Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4330379/ https://ncbi.nlm.nih.gov/pubmed/25605795 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv017 |
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