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Optimization of the PiggyBac Transposon System for the Sustained Genetic Modification of Human T-Lymphocytes
Optimal implementation of adoptive T-cell therapy for cancer will likely require multiple and maintained genetic modifications of the infused T-cells and their progeny so that they home to and recognize tumor cells, overcome tumor immune evasion strategies and remain safe. Retroviral vectors readily...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2796278/ https://ncbi.nlm.nih.gov/pubmed/19752751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e3181ad762b |
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