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Regulation of the antiapoptotic protein cFLIP by the glucocorticoid Dexamethasone in ALL cells
We recently reported that the Smac mimetic BV6 and glucocorticoids, e.g. Dexamethasone (Dexa), synergize to induce cell death in acute lymphoblastic leukemia (ALL) in vitro and in vivo. Here, we discover that this synergism involves Dexa-stimulated downregulation of cellular FLICE-like inhibitory pr...
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| Publié dans: | Oncotarget |
|---|---|
| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Impact Journals LLC
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5893259/ https://ncbi.nlm.nih.gov/pubmed/29662664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24782 |
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