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Induced global deletion of glucocorticoid receptor impairs fracture healing

Although endogenous glucocorticoids (GCs) are important regulators of bone integrity and the immune system, their role in bone repair after fracture—a process highly dependent on inflammation and bone formation—is unclear. Because most effects of GCs are mediated by the glucocorticoid receptor (GR),...

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Библиографические подробности
Опубликовано в: :FASEB J
Главные авторы: Rapp, Anna E., Hachemi, Yasmine, Kemmler, Julia, Koenen, Mascha, Tuckermann, Jan, Ignatius, Anita
Формат: Artigo
Язык:Inglês
Опубликовано: Federation of American Societies for Experimental Biology 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5893166/
https://ncbi.nlm.nih.gov/pubmed/29217668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700459RR
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