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Inhibition of Midkine Augments Osteoporotic Fracture Healing

The heparin-binding growth and differentiation factor midkine (Mdk) is proposed to negatively regulate osteoblast activity and bone formation in the adult skeleton. As Mdk-deficient mice were protected from ovariectomy (OVX)-induced bone loss, this factor may also play a role in the pathogenesis of...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Haffner-Luntzer, Melanie, Kemmler, Julia, Heidler, Verena, Prystaz, Katja, Schinke, Thorsten, Amling, Michael, Kovtun, Anna, Rapp, Anna E., Ignatius, Anita, Liedert, Astrid
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4943649/
https://ncbi.nlm.nih.gov/pubmed/27410432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159278
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