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Midkine-Deficiency Delays Chondrogenesis during the Early Phase of Fracture Healing in Mice

The growth and differentiation factor midkine (Mdk) plays an important role in bone development and remodeling. Mdk-deficient mice display a high bone mass phenotype when aged 12 and 18 months. Furthermore, Mdk has been identified as a negative regulator of mechanically induced bone formation and it...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Haffner-Luntzer, Melanie, Heilmann, Aline, Rapp, Anna Elise, Beie, Simon, Schinke, Thorsten, Amling, Michael, Ignatius, Anita, Liedert, Astrid
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281158/
https://ncbi.nlm.nih.gov/pubmed/25551381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116282
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