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Midkine-Deficiency Delays Chondrogenesis during the Early Phase of Fracture Healing in Mice
The growth and differentiation factor midkine (Mdk) plays an important role in bone development and remodeling. Mdk-deficient mice display a high bone mass phenotype when aged 12 and 18 months. Furthermore, Mdk has been identified as a negative regulator of mechanically induced bone formation and it...
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| Veröffentlicht in: | PLoS One |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4281158/ https://ncbi.nlm.nih.gov/pubmed/25551381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116282 |
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