Induced global deletion of glucocorticoid receptor impairs fracture healing

Although endogenous glucocorticoids (GCs) are important regulators of bone integrity and the immune system, their role in bone repair after fracture—a process highly dependent on inflammation and bone formation—is unclear. Because most effects of GCs are mediated by the glucocorticoid receptor (GR),...

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Bibliographic Details
Published in:FASEB J
Main Authors: Rapp, Anna E., Hachemi, Yasmine, Kemmler, Julia, Koenen, Mascha, Tuckermann, Jan, Ignatius, Anita
Format: Artigo
Language:Inglês
Published: Federation of American Societies for Experimental Biology 2018
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5893166/
https://ncbi.nlm.nih.gov/pubmed/29217668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700459RR
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