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Selective inhibition of histamine-evoked Ca(2+) signals by compartmentalized cAMP in human bronchial airway smooth muscle cells
Intracellular Ca(2+) and cAMP typically cause opposing effects on airway smooth muscle contraction. Receptors that stimulate these pathways are therapeutic targets in asthma and chronic obstructive pulmonary disease. However, the interactions between different G protein-coupled receptors (GPCRs) tha...
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Publicado no: | Cell Calcium |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Elsevier
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5893132/ https://ncbi.nlm.nih.gov/pubmed/29604964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceca.2017.12.002 |
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