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Effects of protein-crystal hydration and temperature on side-chain conformational heterogeneity in monoclinic lysozyme crystals

The modulation of main-chain and side-chain conformational heterogeneity and solvent structure in monoclinic lysozyme crystals by dehydration (related to water activity) and temperature is examined. Decreasing the relative humidity (from 99 to 11%) and decreasing the temperature both lead to contrac...

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Pubblicato in:Acta Crystallogr D Struct Biol
Autori principali: Atakisi, Hakan, Moreau, David W., Thorne, Robert E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Union of Crystallography 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5892876/
https://ncbi.nlm.nih.gov/pubmed/29652254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2059798318000207
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