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Ligand binding remodels protein side-chain conformational heterogeneity

While protein conformational heterogeneity plays an important role in many aspects of biological function, including ligand binding, its impact has been difficult to quantify. Macromolecular X-ray diffraction is commonly interpreted with a static structure, but it can provide information on both the...

詳細記述

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書誌詳細
主要な著者: Stephanie A Wankowicz, Saulo H de Oliveira, Daniel W Hogan, Henry van den Bedem, James S Fraser
フォーマット: Artigo
言語:Inglês
出版事項: eLife Sciences Publications Ltd 2022-03-01
シリーズ:eLife
主題:
オンライン・アクセス:https://elifesciences.org/articles/74114
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