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Solvent flows, conformation changes and lattice reordering in a cold protein crystal

When protein crystals are abruptly cooled, the unit-cell, protein and solvent-cavity volumes all contract, but the volume of bulk-like internal solvent may expand. Outflow of this solvent from the unit cell and its accumulation in defective interior crystal regions has been suggested as one cause of...

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Detalhes bibliográficos
Publicado no:Acta Crystallogr D Struct Biol
Main Authors: Moreau, David W., Atakisi, Hakan, Thorne, Robert E.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6834080/
https://ncbi.nlm.nih.gov/pubmed/31692472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2059798319013822
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