Erythrosin B is a potent and broad-spectrum orthosteric inhibitor of the flavivirus NS2B-NS3 protease

Many flaviviruses, such as Zika virus (ZIKV), Dengue virus (DENV1-4) and yellow fever virus (YFV), are significant human pathogens. Infection with ZIKV, an emerging mosquito-borne flavivirus, is associated with increased risk of microcephaly in newborns and Guillain-Barré syndrome and other complica...

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Publicado en:Antiviral Res
Main Authors: Li, Zhong, Sakamuru, Srilatha, Huang, Ruili, Brecher, Matthew, Koetzner, Cheri A., Zhang, Jing, Chen, Haiying, Qin, Cheng-feng, Zhang, Qing-Yu, Zhou, Jia, Kramer, Laura D., Xia, Menghang, Li, Hongmin
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5892443/
https://ncbi.nlm.nih.gov/pubmed/29288700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2017.12.018
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