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Expression of Pyridoxal 5′-Phosphate-Independent Racemases Can Reduce 2-Aminoacrylate Stress in Salmonella enterica

The RidA protein (PF01042) from Salmonella enterica is a deaminase that quenches 2-aminoacrylate (2AA) and other reactive metabolites. In the absence of RidA, 2AA accumulates, damages cellular enzymes, and compromises the metabolic network. In vitro, RidA homologs from all domains of life deaminate...

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Foilsithe in:J Bacteriol
Main Authors: Hodge-Hanson, Kelsey M., Zoino, Allison, Downs, Diana M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5892117/
https://ncbi.nlm.nih.gov/pubmed/29440254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00751-17
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