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Endogenous Synthesis of 2-Aminoacrylate Contributes to Cysteine Sensitivity in Salmonella enterica

RidA, the archetype member of the widely conserved RidA/YER057c/UK114 family of proteins, prevents reactive enamine/imine intermediates from accumulating in Salmonella enterica by catalyzing their hydrolysis to stable keto acid products. In the absence of RidA, endogenous 2-aminoacrylate persists in...

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Détails bibliographiques
Auteurs principaux: Ernst, Dustin C., Lambrecht, Jennifer A., Schomer, Rebecca A., Downs, Diana M.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135687/
https://ncbi.nlm.nih.gov/pubmed/25002544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01960-14
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