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Expression of Pyridoxal 5′-Phosphate-Independent Racemases Can Reduce 2-Aminoacrylate Stress in Salmonella enterica
The RidA protein (PF01042) from Salmonella enterica is a deaminase that quenches 2-aminoacrylate (2AA) and other reactive metabolites. In the absence of RidA, 2AA accumulates, damages cellular enzymes, and compromises the metabolic network. In vitro, RidA homologs from all domains of life deaminate...
Tallennettuna:
| Julkaisussa: | J Bacteriol |
|---|---|
| Päätekijät: | , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society for Microbiology
2018
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5892117/ https://ncbi.nlm.nih.gov/pubmed/29440254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00751-17 |
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