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Extra-telomeric functions of telomerase in the pathogenesis of Epstein-Barr virus-driven B-cell malignancies and potential therapeutic implications

The Epstein-Barr virus (EBV) is a ubiquitous human γ-herpesvirus causally linked to a broad spectrum of both lymphoid and epithelial malignancies. In order to maintain its persistence in host cells and promote tumorigenesis, EBV must restrict its lytic cycle, which would ultimately lead to cell deat...

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發表在:Infect Agent Cancer
Main Authors: Giunco, Silvia, Petrara, Maria Raffaella, Zangrossi, Manuela, Celeghin, Andrea, De Rossi, Anita
格式: Artigo
語言:Inglês
出版: BioMed Central 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5892012/
https://ncbi.nlm.nih.gov/pubmed/29643934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13027-018-0186-5
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