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Extra-telomeric functions of telomerase in the pathogenesis of Epstein-Barr virus-driven B-cell malignancies and potential therapeutic implications

The Epstein-Barr virus (EBV) is a ubiquitous human γ-herpesvirus causally linked to a broad spectrum of both lymphoid and epithelial malignancies. In order to maintain its persistence in host cells and promote tumorigenesis, EBV must restrict its lytic cycle, which would ultimately lead to cell deat...

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Библиографические подробности
Опубликовано в: :Infect Agent Cancer
Главные авторы: Giunco, Silvia, Petrara, Maria Raffaella, Zangrossi, Manuela, Celeghin, Andrea, De Rossi, Anita
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5892012/
https://ncbi.nlm.nih.gov/pubmed/29643934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13027-018-0186-5
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