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Extra-telomeric functions of telomerase in the pathogenesis of Epstein-Barr virus-driven B-cell malignancies and potential therapeutic implications

The Epstein-Barr virus (EBV) is a ubiquitous human γ-herpesvirus causally linked to a broad spectrum of both lymphoid and epithelial malignancies. In order to maintain its persistence in host cells and promote tumorigenesis, EBV must restrict its lytic cycle, which would ultimately lead to cell deat...

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Podrobná bibliografie
Vydáno v:Infect Agent Cancer
Hlavní autoři: Giunco, Silvia, Petrara, Maria Raffaella, Zangrossi, Manuela, Celeghin, Andrea, De Rossi, Anita
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5892012/
https://ncbi.nlm.nih.gov/pubmed/29643934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13027-018-0186-5
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