Epstein-Barr virus and telomerase: from cell immortalization to therapy

Overcoming cellular senescence is strictly required for virus-driven tumors, including those associated with Epstein-Barr virus (EBV). This critical step is successfully accomplished by EBV through TERT expression and telomerase activation in infected cells. We herein review the complex interplay be...

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Main Authors: Dolcetti, Riccardo, Giunco, Silvia, Dal Col, Jessica, Celeghin, Andrea, Mastorci, Katy, De Rossi, Anita
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Review
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943417/
https://ncbi.nlm.nih.gov/pubmed/24572088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-9378-9-8
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