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Cross talk between EBV and telomerase: the role of TERT and NOTCH2 in the switch of latent/lytic cycle of the virus

Epstein–Barr virus (EBV)-associated malignancies, as well as lymphoblastoid cell lines (LCLs), obtained in vitro by EBV infection of B cells, express latent viral proteins and maintain their ability to grow indefinitely through inappropriate activation of telomere-specific reverse transcriptase (TER...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Giunco, S, Celeghin, A, Gianesin, K, Dolcetti, R, Indraccolo, S, De Rossi, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669716/
https://ncbi.nlm.nih.gov/pubmed/26018735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.145
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