Latent Membrane Protein 1 of Epstein-Barr Virus Activates the hTERT Promoter and Enhances Telomerase Activity in B Lymphocytes

Transformation of primary B lymphocytes by Epstein-Barr virus requires the establishment of a strictly latent infection, the expression of several latent viral proteins, and sustained telomerase activity. Our previous findings indicated that induction of hTERT, the rate-limiting catalytic unit of th...

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Detalhes bibliográficos
Main Authors: Terrin, Liliana, Dal Col, Jessica, Rampazzo, Enrica, Zancai, Paola, Pedrotti, Moreno, Ammirabile, Grazia, Bergamin, Stefano, Rizzo, Silvana, Dolcetti, Riccardo, De Rossi, Anita
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Transformation and Oncogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2566252/
https://ncbi.nlm.nih.gov/pubmed/18684838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00321-08
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