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hTERT promotes cell adhesion and migration independent of telomerase activity

hTERT, a catalytic component of human telomerase, is undetectable in normal somatic cells but up-regulated in cancer and stem cells where telomere length is maintained by telomerase. Accumulated evidence indicates that hTERT may have noncanonical functions beyond telomerase by regulating the express...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Liu, Haiying, Liu, Qianqian, Ge, Yuanlong, Zhao, Qi, Zheng, Xiaohui, Zhao, Yong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4789728/
https://ncbi.nlm.nih.gov/pubmed/26971878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22886
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