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hTERT promotes cell adhesion and migration independent of telomerase activity

hTERT, a catalytic component of human telomerase, is undetectable in normal somatic cells but up-regulated in cancer and stem cells where telomere length is maintained by telomerase. Accumulated evidence indicates that hTERT may have noncanonical functions beyond telomerase by regulating the express...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Liu, Haiying, Liu, Qianqian, Ge, Yuanlong, Zhao, Qi, Zheng, Xiaohui, Zhao, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4789728/
https://ncbi.nlm.nih.gov/pubmed/26971878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22886
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