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hTERT methylation is necessary but not sufficient for telomerase activity in colorectal cells
Colorectal cancers exhibit a high telomerase activity, usually correlated with the hypermethylation of the promoter of its hTERT catalytic subunit. Although telomerase is not expressed in normal tissue, certain proliferative somatic cells such as intestinal crypt cells have demonstrated telomerase a...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
D.A. Spandidos
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3406488/ https://ncbi.nlm.nih.gov/pubmed/22848298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2011.386 |
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