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hTERT methylation is necessary but not sufficient for telomerase activity in colorectal cells

Colorectal cancers exhibit a high telomerase activity, usually correlated with the hypermethylation of the promoter of its hTERT catalytic subunit. Although telomerase is not expressed in normal tissue, certain proliferative somatic cells such as intestinal crypt cells have demonstrated telomerase a...

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Detalhes bibliográficos
Main Authors: VALLS-BAUTISTA, CRISTINA, BOUGEL, STÉPHANIE, PIÑOL-FELIS, CARME, VIÑAS-SALAS, JOAN, BENHATTAR, JEAN
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406488/
https://ncbi.nlm.nih.gov/pubmed/22848298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2011.386
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