BORIS/CTCFL-mediated transcriptional regulation of the hTERT telomerase gene in testicular and ovarian tumor cells

Telomerase activity, not detectable in somatic cells but frequently activated during carcinogenesis, confers immortality to tumors. Mechanisms governing expression of the catalytic subunit hTERT, the limiting factor for telomerase activity, still remain unclear. We previously proposed a model in whi...

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Autors principals: Renaud, Stéphanie, Loukinov, Dmitri, Alberti, Loredana, Vostrov, Alexander, Kwon, Yoo-Wook, Bosman, Fred T., Lobanenkov, Victor, Benhattar, Jean
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2011
Matèries:
Gene Regulation, Chromatin and Epigenetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035453/
https://ncbi.nlm.nih.gov/pubmed/20876690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq827
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