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BORIS/CTCFL-mediated transcriptional regulation of the hTERT telomerase gene in testicular and ovarian tumor cells

Telomerase activity, not detectable in somatic cells but frequently activated during carcinogenesis, confers immortality to tumors. Mechanisms governing expression of the catalytic subunit hTERT, the limiting factor for telomerase activity, still remain unclear. We previously proposed a model in whi...

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Bibliografiske detaljer
Main Authors: Renaud, Stéphanie, Loukinov, Dmitri, Alberti, Loredana, Vostrov, Alexander, Kwon, Yoo-Wook, Bosman, Fred T., Lobanenkov, Victor, Benhattar, Jean
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035453/
https://ncbi.nlm.nih.gov/pubmed/20876690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq827
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