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Proteomic profiling of VCP substrates links VCP to K6‐linked ubiquitylation and c‐Myc function

Valosin‐containing protein (VCP) is an evolutionarily conserved ubiquitin‐dependent ATPase that mediates the degradation of proteins through the ubiquitin–proteasome pathway. Despite the central role of VCP in the regulation of protein homeostasis, identity and nature of its cellular substrates rema...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Heidelberger, Jan B, Voigt, Andrea, Borisova, Marina E, Petrosino, Giuseppe, Ruf, Stefanie, Wagner, Sebastian A, Beli, Petra
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5891417/
https://ncbi.nlm.nih.gov/pubmed/29467282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201744754
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