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Mass Spectrometry-Based Proteomics for Investigating DNA Damage-Associated Protein Ubiquitylation

Modification of proteins with the 76 amino acid protein ubiquitin plays essential roles in cellular signaling. Development of methods for specific enrichment of ubiquitin remnant peptides and advances in high-resolution mass spectrometry have enabled proteome-wide identification of endogenous ubiqui...

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Détails bibliographiques
Publié dans:Front Genet
Auteurs principaux: Heidelberger, Jan B., Wagner, Sebastian A., Beli, Petra
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905943/
https://ncbi.nlm.nih.gov/pubmed/27379159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2016.00109
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