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Proteomic profiling of VCP substrates links VCP to K6‐linked ubiquitylation and c‐Myc function

Valosin‐containing protein (VCP) is an evolutionarily conserved ubiquitin‐dependent ATPase that mediates the degradation of proteins through the ubiquitin–proteasome pathway. Despite the central role of VCP in the regulation of protein homeostasis, identity and nature of its cellular substrates rema...

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Detalles Bibliográficos
Publicado en:EMBO Rep
Main Authors: Heidelberger, Jan B, Voigt, Andrea, Borisova, Marina E, Petrosino, Giuseppe, Ruf, Stefanie, Wagner, Sebastian A, Beli, Petra
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5891417/
https://ncbi.nlm.nih.gov/pubmed/29467282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201744754
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