Novel selective agents for the degradation of androgen receptor variants to treat castration-resistant prostate cancer

Androgen receptor (AR) mediates the growth of prostate cancer (PCa) throughout its course of development, including in abnormal splice variants (AR-SV)-driven advanced stage castration-resistant disease. AR stabilization by androgens makes it distinct from other steroid receptors, which are typicall...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancer Res
Egile Nagusiak: Ponnusamy, Suriyan, Coss, Christopher C., Thiyagarajan, Thirumagal, Watts, Kate, Hwang, Dong-Jin, He, Yali, Selth, Luke A., McEwan, Iain J., Duke, Charles B., Pagadala, Jayaprakash, Singh, Geetika, Wake, Robert W., Ledbetter, Christopher, Tilley, Wayne D., Moldoveanu, Tudor, Dalton, James T., Miller, Duane D., Narayanan, Ramesh
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890913/
https://ncbi.nlm.nih.gov/pubmed/28978635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-0976
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