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β-Cell dysfunction in diabetes: a crisis of identity?

Type 2 diabetes is characterized by insulin resistance and a progressive loss of β-cell function induced by a combination of both β-cell loss and impaired insulin secretion from remaining β-cells. Here we review the fate of the β-cell under chronic hyperglycaemic conditions with regard to β-cell mas...

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Dettagli Bibliografici
Pubblicato in:Diabetes Obes Metab
Autori principali: Brereton, Melissa F, Rohm, Maria, Ashcroft, Frances M
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890905/
https://ncbi.nlm.nih.gov/pubmed/27615138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/dom.12732
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