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Hyperglycaemia induces metabolic dysfunction and glycogen accumulation in pancreatic β-cells
Insulin secretion from pancreatic β-cells is impaired in all forms of diabetes. The resultant hyperglycaemia has deleterious effects on many tissues, including β-cells. Here we show that chronic hyperglycaemia impairs glucose metabolism and alters expression of metabolic genes in pancreatic islets....
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Nat Commun |
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| Prif Awduron: | , , , , , , , , , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Nature Publishing Group
2016
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5123088/ https://ncbi.nlm.nih.gov/pubmed/27882918 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13496 |
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