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Pancreatic β-Cell Electrical Activity and Insulin Secretion: Of Mice and Men

The pancreatic β-cell plays a key role in glucose homeostasis by secreting insulin, the only hormone capable of lowering the blood glucose concentration. Impaired insulin secretion results in the chronic hyperglycemia that characterizes type 2 diabetes (T2DM), which currently afflicts >450 millio...

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Detalles Bibliográficos
Publicado en:Physiol Rev
Main Authors: Rorsman, Patrik, Ashcroft, Frances M.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866358/
https://ncbi.nlm.nih.gov/pubmed/29212789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physrev.00008.2017
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