PPARβ/δ affects pancreatic β cell mass and insulin secretion in mice

PPARβ/δ protects against obesity by reducing dyslipidemia and insulin resistance via effects in muscle, adipose tissue, and liver. However, its function in pancreas remains ill defined. To gain insight into its hypothesized role in β cell function, we specifically deleted Pparb/d in the epithelial c...

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Detalhes bibliográficos
Main Authors: Iglesias, José, Barg, Sebastian, Vallois, David, Lahiri, Shawon, Roger, Catherine, Yessoufou, Akadiri, Pradevand, Sylvain, McDonald, Angela, Bonal, Claire, Reimann, Frank, Gribble, Fiona, Debril, Marie-Bernard, Metzger, Daniel, Chambon, Pierre, Herrera, Pedro, Rutter, Guy A., Prentki, Marc, Thorens, Bernard, Wahli, Walter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484427/
https://ncbi.nlm.nih.gov/pubmed/23093780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI42127
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