PPARβ/δ affects pancreatic β cell mass and insulin secretion in mice

PPARβ/δ protects against obesity by reducing dyslipidemia and insulin resistance via effects in muscle, adipose tissue, and liver. However, its function in pancreas remains ill defined. To gain insight into its hypothesized role in β cell function, we specifically deleted Pparb/d in the epithelial c...

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Autors principals: Iglesias, José, Barg, Sebastian, Vallois, David, Lahiri, Shawon, Roger, Catherine, Yessoufou, Akadiri, Pradevand, Sylvain, McDonald, Angela, Bonal, Claire, Reimann, Frank, Gribble, Fiona, Debril, Marie-Bernard, Metzger, Daniel, Chambon, Pierre, Herrera, Pedro, Rutter, Guy A., Prentki, Marc, Thorens, Bernard, Wahli, Walter
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484427/
https://ncbi.nlm.nih.gov/pubmed/23093780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI42127
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