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PPARβ/δ affects pancreatic β cell mass and insulin secretion in mice
PPARβ/δ protects against obesity by reducing dyslipidemia and insulin resistance via effects in muscle, adipose tissue, and liver. However, its function in pancreas remains ill defined. To gain insight into its hypothesized role in β cell function, we specifically deleted Pparb/d in the epithelial c...
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| Główni autorzy: | , , , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Clinical Investigation
2012
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3484427/ https://ncbi.nlm.nih.gov/pubmed/23093780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI42127 |
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