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PPARβ/δ affects pancreatic β cell mass and insulin secretion in mice
PPARβ/δ protects against obesity by reducing dyslipidemia and insulin resistance via effects in muscle, adipose tissue, and liver. However, its function in pancreas remains ill defined. To gain insight into its hypothesized role in β cell function, we specifically deleted Pparb/d in the epithelial c...
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| Asıl Yazarlar: | , , , , , , , , , , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Clinical Investigation
2012
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3484427/ https://ncbi.nlm.nih.gov/pubmed/23093780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI42127 |
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