PPARβ/δ affects pancreatic β cell mass and insulin secretion in mice

PPARβ/δ protects against obesity by reducing dyslipidemia and insulin resistance via effects in muscle, adipose tissue, and liver. However, its function in pancreas remains ill defined. To gain insight into its hypothesized role in β cell function, we specifically deleted Pparb/d in the epithelial c...

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Bibliografski detalji
Glavni autori: Iglesias, José, Barg, Sebastian, Vallois, David, Lahiri, Shawon, Roger, Catherine, Yessoufou, Akadiri, Pradevand, Sylvain, McDonald, Angela, Bonal, Claire, Reimann, Frank, Gribble, Fiona, Debril, Marie-Bernard, Metzger, Daniel, Chambon, Pierre, Herrera, Pedro, Rutter, Guy A., Prentki, Marc, Thorens, Bernard, Wahli, Walter
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2012
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484427/
https://ncbi.nlm.nih.gov/pubmed/23093780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI42127
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