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Validated Method for the Quantification of Baclofen in Human Plasma Using Solid-Phase Extraction and Liquid Chromatography–Tandem Mass Spectrometry

A highly sensitive and fully validated method was developed for the quantification of baclofen in human plasma. After adjusting the pH of the plasma samples using a phosphate buffer solution (pH 4), baclofen was purified using mixed mode (C8/cation exchange) solid-phase extraction (SPE) cartridges....

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Bibliografski detalji
Izdano u:J Anal Toxicol
Glavni autori: Nahar, Limon Khatun, Cordero, Rosa Elena, Nutt, David, Lingford-Hughes, Anne, Turton, Samuel, Durant, Claire, Wilson, Sue, Paterson, Sue
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890835/
https://ncbi.nlm.nih.gov/pubmed/26538544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jat/bkv125
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