Pharmacodynamics of dose-escalated ‘front-loading’ polymyxin B regimens against polymyxin-resistant mcr-1-harbouring Escherichia coli

Objectives: Gram-negative bacteria harbouring the mcr-1 plasmid are resistant to the ‘last-line’ polymyxins and have been reported worldwide. Our objective was to define the impact of increasing the initial polymyxin B dose intensity against an mcr-1-harbouring strain to delineate the impact of plas...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Antimicrob Chemother
Päätekijät: Smith, Nicholas M., Bulman, Zackery P., Sieron, Arthur O., Bulitta, Jürgen B., Holden, Patricia N., Nation, Roger L., Li, Jian, Wright, Gerard D., Tsuji, Brian T.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2017
Aiheet:
Original Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890756/
https://ncbi.nlm.nih.gov/pubmed/28505268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkx121
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia