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Pharmacodynamics of dose-escalated ‘front-loading’ polymyxin B regimens against polymyxin-resistant mcr-1-harbouring Escherichia coli
Objectives: Gram-negative bacteria harbouring the mcr-1 plasmid are resistant to the ‘last-line’ polymyxins and have been reported worldwide. Our objective was to define the impact of increasing the initial polymyxin B dose intensity against an mcr-1-harbouring strain to delineate the impact of plas...
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| Publicado no: | J Antimicrob Chemother |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5890756/ https://ncbi.nlm.nih.gov/pubmed/28505268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkx121 |
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