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Fitness cost constrains the spectrum of marR mutations in ciprofloxacin-resistant Escherichia coli
OBJECTIVES: To determine whether the spectrum of mutations in marR in ciprofloxacin-resistant clinical isolates of Escherichia coli shows evidence of selection bias, either to reduce fitness costs, or to increase drug resistance. MarR is a repressor protein that regulates, via MarA, expression of th...
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| Yayımlandı: | J Antimicrob Chemother |
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| Asıl Yazarlar: | , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Oxford University Press
2017
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5890708/ https://ncbi.nlm.nih.gov/pubmed/28962020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkx270 |
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