Mutation Supply and Relative Fitness Shape the Genotypes of Ciprofloxacin-Resistant Escherichia coli

Ciprofloxacin is an important antibacterial drug targeting Type II topoisomerases, highly active against Gram-negatives including Escherichia coli. The evolution of resistance to ciprofloxacin in E. coli always requires multiple genetic changes, usually including mutations affecting two different dr...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Biol Evol
Main Authors: Huseby, Douglas L., Pietsch, Franziska, Brandis, Gerrit, Garoff, Linnéa, Tegehall, Angelica, Hughes, Diarmaid
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2017
Teme:
Discoveries
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400412/
https://ncbi.nlm.nih.gov/pubmed/28087782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msx052
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki