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Fitness cost constrains the spectrum of marR mutations in ciprofloxacin-resistant Escherichia coli
OBJECTIVES: To determine whether the spectrum of mutations in marR in ciprofloxacin-resistant clinical isolates of Escherichia coli shows evidence of selection bias, either to reduce fitness costs, or to increase drug resistance. MarR is a repressor protein that regulates, via MarA, expression of th...
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| Publicat a: | J Antimicrob Chemother |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5890708/ https://ncbi.nlm.nih.gov/pubmed/28962020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkx270 |
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