Multicentre study of posaconazole delayed-release tablet serum level and association with hepatotoxicity and QTc prolongation

Objectives: The association of posaconazole serum concentrations and toxicity is unclear. An assessment of whether levels obtained with the delayed-release tablet (DRT) formulation are correlated with abnormal liver function test (LFT) results and/or QTc prolongation was undertaken. Methods: This wa...

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Bibliografiset tiedot
Julkaisussa:J Antimicrob Chemother
Päätekijät: Pettit, Natasha N., Miceli, Marisa H., Rivera, Christina G., Narayanan, Prasanna P., Perissinotti, Anthony J., Hsu, Meier, Delacruz, Jennifer, Gedrimaite, Zivile, Han, Zhe, Steinbeck, Jennifer, Pisano, Jennifer, Seo, Susan K., Paskovaty, Alla
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2017
Aiheet:
Original Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890703/
https://ncbi.nlm.nih.gov/pubmed/28475803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkx122
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