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Multicentre study of posaconazole delayed-release tablet serum level and association with hepatotoxicity and QTc prolongation

Objectives: The association of posaconazole serum concentrations and toxicity is unclear. An assessment of whether levels obtained with the delayed-release tablet (DRT) formulation are correlated with abnormal liver function test (LFT) results and/or QTc prolongation was undertaken. Methods: This wa...

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Bibliografiske detaljer
Udgivet i:J Antimicrob Chemother
Main Authors: Pettit, Natasha N., Miceli, Marisa H., Rivera, Christina G., Narayanan, Prasanna P., Perissinotti, Anthony J., Hsu, Meier, Delacruz, Jennifer, Gedrimaite, Zivile, Han, Zhe, Steinbeck, Jennifer, Pisano, Jennifer, Seo, Susan K., Paskovaty, Alla
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890703/
https://ncbi.nlm.nih.gov/pubmed/28475803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkx122
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