Multicentre study of posaconazole delayed-release tablet serum level and association with hepatotoxicity and QTc prolongation

Objectives: The association of posaconazole serum concentrations and toxicity is unclear. An assessment of whether levels obtained with the delayed-release tablet (DRT) formulation are correlated with abnormal liver function test (LFT) results and/or QTc prolongation was undertaken. Methods: This wa...

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Detalhes bibliográficos
Publicado no:J Antimicrob Chemother
Main Authors: Pettit, Natasha N., Miceli, Marisa H., Rivera, Christina G., Narayanan, Prasanna P., Perissinotti, Anthony J., Hsu, Meier, Delacruz, Jennifer, Gedrimaite, Zivile, Han, Zhe, Steinbeck, Jennifer, Pisano, Jennifer, Seo, Susan K., Paskovaty, Alla
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890703/
https://ncbi.nlm.nih.gov/pubmed/28475803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkx122
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