The oscillation of intracellular Ca(2+) influx associated with the circadian expression of Piezo1 and TRPV4 in the bladder urothelium

We previously showed that bladder functions are controlled by clock genes with circadian rhythm. The sensation of bladder fullness (SBF) is sensed by mechano-sensor such as Piezo1 and TRPV4 in the mouse bladder urothelium. However, functional circadian rhythms of such mechano-sensors remain unknown....

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Pubblicato in:Sci Rep
Autori principali: Ihara, Tatsuya, Mitsui, Takahiko, Nakamura, Yuki, Kanda, Mie, Tsuchiya, Sachiko, Kira, Satoru, Nakagomi, Hiroshi, Sawada, Norifumi, Kamiyama, Manabu, Hirayama, Yuri, Shigetomi, Eiji, Shinozaki, Youichi, Yoshiyama, Mitsuharu, Nakao, Atsuhito, Takeda, Masayuki, Koizumi, Schuichi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890282/
https://ncbi.nlm.nih.gov/pubmed/29632308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23115-w
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