Intermittent restraint stress induces circadian misalignment in the mouse bladder, leading to nocturia

Intermittent stress disrupts the circadian rhythm in clock genes such as Per2 only in peripheral organs without any effect on the central circadian clock in the suprachiasmatic nucleus. Here, the effect of restraint stress (RS) on circadian bladder function was investigated based on urination behavi...

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Vydáno v:Sci Rep
Hlavní autoři: Ihara, Tatsuya, Nakamura, Yuki, Mitsui, Takahiko, Tsuchiya, Sachiko, Kanda, Mie, Kira, Satoru, Nakagomi, Hiroshi, Sawada, Norifumi, Kamiyama, Manabu, Shigetomi, Eiji, Shinozaki, Youichi, Yoshiyama, Mitsuharu, Nakao, Atsuhito, Koizumi, Schuichi, Takeda, Masayuki
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6624370/
https://ncbi.nlm.nih.gov/pubmed/31296902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46517-w
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