Intermittent restraint stress induces circadian misalignment in the mouse bladder, leading to nocturia

Intermittent stress disrupts the circadian rhythm in clock genes such as Per2 only in peripheral organs without any effect on the central circadian clock in the suprachiasmatic nucleus. Here, the effect of restraint stress (RS) on circadian bladder function was investigated based on urination behavi...

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Publicat a:Sci Rep
Autors principals: Ihara, Tatsuya, Nakamura, Yuki, Mitsui, Takahiko, Tsuchiya, Sachiko, Kanda, Mie, Kira, Satoru, Nakagomi, Hiroshi, Sawada, Norifumi, Kamiyama, Manabu, Shigetomi, Eiji, Shinozaki, Youichi, Yoshiyama, Mitsuharu, Nakao, Atsuhito, Koizumi, Schuichi, Takeda, Masayuki
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6624370/
https://ncbi.nlm.nih.gov/pubmed/31296902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46517-w
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