The oscillation of intracellular Ca(2+) influx associated with the circadian expression of Piezo1 and TRPV4 in the bladder urothelium

We previously showed that bladder functions are controlled by clock genes with circadian rhythm. The sensation of bladder fullness (SBF) is sensed by mechano-sensor such as Piezo1 and TRPV4 in the mouse bladder urothelium. However, functional circadian rhythms of such mechano-sensors remain unknown....

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ihara, Tatsuya, Mitsui, Takahiko, Nakamura, Yuki, Kanda, Mie, Tsuchiya, Sachiko, Kira, Satoru, Nakagomi, Hiroshi, Sawada, Norifumi, Kamiyama, Manabu, Hirayama, Yuri, Shigetomi, Eiji, Shinozaki, Youichi, Yoshiyama, Mitsuharu, Nakao, Atsuhito, Takeda, Masayuki, Koizumi, Schuichi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890282/
https://ncbi.nlm.nih.gov/pubmed/29632308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23115-w
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