Functional Role for Piezo1 in Stretch-evoked Ca(2+) Influx and ATP Release in Urothelial Cell Cultures

The urothelium is a sensory structure that contributes to mechanosensation in the urinary bladder. Here, we provide evidence for a critical role for the Piezo1 channel, a newly identified mechanosensory molecule, in the mouse bladder urothelium. We performed a systematic analysis of the molecular an...

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Detalhes bibliográficos
Main Authors: Miyamoto, Tatsuya, Mochizuki, Tsutomu, Nakagomi, Hiroshi, Kira, Satoru, Watanabe, Masaki, Takayama, Yasunori, Suzuki, Yoshiro, Koizumi, Schuichi, Takeda, Masayuki, Tominaga, Makoto
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047422/
https://ncbi.nlm.nih.gov/pubmed/24759099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.528638
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